Pesquisa sobre:
PROTEASOME ENDOPEPTIDASE COMPLEX
Descritores Encontrados:
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DeCS
Descritor
Inglês
:
Proteasome Endopeptidase Complex
Descritor
Espanhol
:
Complejo de la Endopetidasa Proteasomal
Descritor
Português
:
Complexo de Endopeptidases do Proteassoma
Categoria:
D05.500.562.500
D08.811.277.656.918
D08.811.600.730
Definição
Inglês
:
A large multisubunit complex that plays an important
role
in the degradation of most of the cytosolic and
nuclear proteins
in
eukaryotic cells
. It contains a 700-kDa catalytic sub-complex and two 700-kDa regulatory sub-complexes. The complex digests
ubiquitinated proteins
and protein activated via
ornithine decarboxylase
antizyme.
Combinados
Inglês
:
Proteasome Endopeptidase Complex
/
antagonists & inhibitors
use
Proteasome Inhibitors
Relacionados
Inglês
:
Ubiquitin-Protein Ligase Complexes
Nota Histórica
Inglês
:
2005; use PROTEASOME ENDOPEPTIDASE COMPLEX (NM) 1986-2004
Qualificadores Permitidos
Inglês
:
AD
administration & dosage
AE
adverse effects
AN
analysis
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Número do Registro:
38685
Identificador Único:
D046988
Ocorrência na BVS
:
Similar:
DeCS
CID-10
SciELO
LILACS
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